Purified Anti-Human CD45RO (UCHL1)
The UCHL1 antibody reacts with the human CD45 isoform known as CD45RO, a protein tyrosine phosphatase of ≥ 220 kDa. CD45 is one of the most abundant hematopoietic markers, and is expressed on all leukocytes (the Leukocyte Common Antigen, LCA). Various isoforms are generated and expressed in cell-specific patterns. With their broad cell distribution, CD45 isoforms are critical for many leukocyte functions, regulating signal transduction and cell activation associated with the T cell receptor, B cell receptor, and IL-2 receptor. Other forms of CD45, with restricted cellular expression, include CD45R (B220), CD45RA and CD45RB./p>
The UCHL1 antibody is widely used as a marker for human CD45RO expression on thymocytes, activated memory T cells, monocytes, macrophages and granulocytes. The antibody is reported to be cross-reactive for Chimpanzee CD45RO.
| Name | Purified Anti-Human CD45RO (UCHL1) |
|---|---|
| Cat. No. | 70-0457 |
| Gene ID | 5788 |
| Clone | UCHL1 |
| Isotype | Mouse IgG2a, κ |
| Reactivity | Human |
| Cross Reactivity | Chimpanzee |
| Format | Purified |
| Application | Flow Cytometry, IF, IHCF, IHCP, IP, Western Blot |
Original: $55.00
-70%$55.00
$16.50Purified Anti-Human CD45RO (UCHL1)
The UCHL1 antibody reacts with the human CD45 isoform known as CD45RO, a protein tyrosine phosphatase of ≥ 220 kDa. CD45 is one of the most abundant hematopoietic markers, and is expressed on all leukocytes (the Leukocyte Common Antigen, LCA). Various isoforms are generated and expressed in cell-specific patterns. With their broad cell distribution, CD45 isoforms are critical for many leukocyte functions, regulating signal transduction and cell activation associated with the T cell receptor, B cell receptor, and IL-2 receptor. Other forms of CD45, with restricted cellular expression, include CD45R (B220), CD45RA and CD45RB./p>
The UCHL1 antibody is widely used as a marker for human CD45RO expression on thymocytes, activated memory T cells, monocytes, macrophages and granulocytes. The antibody is reported to be cross-reactive for Chimpanzee CD45RO.
| Name | Purified Anti-Human CD45RO (UCHL1) |
|---|---|
| Cat. No. | 70-0457 |
| Gene ID | 5788 |
| Clone | UCHL1 |
| Isotype | Mouse IgG2a, κ |
| Reactivity | Human |
| Cross Reactivity | Chimpanzee |
| Format | Purified |
| Application | Flow Cytometry, IF, IHCF, IHCP, IP, Western Blot |
Product Information
Product Information
Shipping & Returns
Shipping & Returns
Description
The UCHL1 antibody reacts with the human CD45 isoform known as CD45RO, a protein tyrosine phosphatase of ≥ 220 kDa. CD45 is one of the most abundant hematopoietic markers, and is expressed on all leukocytes (the Leukocyte Common Antigen, LCA). Various isoforms are generated and expressed in cell-specific patterns. With their broad cell distribution, CD45 isoforms are critical for many leukocyte functions, regulating signal transduction and cell activation associated with the T cell receptor, B cell receptor, and IL-2 receptor. Other forms of CD45, with restricted cellular expression, include CD45R (B220), CD45RA and CD45RB./p>
The UCHL1 antibody is widely used as a marker for human CD45RO expression on thymocytes, activated memory T cells, monocytes, macrophages and granulocytes. The antibody is reported to be cross-reactive for Chimpanzee CD45RO.
| Name | Purified Anti-Human CD45RO (UCHL1) |
|---|---|
| Cat. No. | 70-0457 |
| Gene ID | 5788 |
| Clone | UCHL1 |
| Isotype | Mouse IgG2a, κ |
| Reactivity | Human |
| Cross Reactivity | Chimpanzee |
| Format | Purified |
| Application | Flow Cytometry, IF, IHCF, IHCP, IP, Western Blot |
