APC Anti-Human CD14 (61D3)
The 61D3 antibody is specific for human CD14, a 53-55 kDa GPI-anchored glycoprotein. CD14 is highly expressed on monocytes and to a lesser extent on interfollicular macrophages, and some dendritic cells. Together with LPS-Binding Protein (LBP), CD14 binds to and mediates the innate immune response to bacterial lipopolysaccharide (LPS).
Ā
Recent Citations:
McMurray JL, von Borstel A, Taher TE, Syrimi E, Taylor GS, Sharif M, Rossjohn J, Remmerswaal EBM, Bemelman FJ, Vieira Braga FA, Chen X, Teichmann SA, Mohammed F, Berry AA, Lyke KE, Williamson KC, Stubbington MJT, Davey MS, Willcox CR, Willcox BE. Transcriptional profiling of human VĪ“1 TĀ cells reveals a pathogen-driven adaptive differentiation program. Cell Rep. 2022 May 24;39(8):110858. doi: 10.1016/j.celrep.2022.110858. PMID: 35613583.
| Name | APC Anti-Human CD14 (61D3) |
|---|---|
| Cat. No. | 20-0149 |
| Alternative Names | LPS-R, Mo2 |
| Gene ID | 929 |
| Clone | 61D3 |
| Isotype | Mouse IgG1, kappa |
| Reactivity | Human |
| Format | APC |
| Application | Flow Cytometry |
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APC Anti-Human CD14 (61D3)
The 61D3 antibody is specific for human CD14, a 53-55 kDa GPI-anchored glycoprotein. CD14 is highly expressed on monocytes and to a lesser extent on interfollicular macrophages, and some dendritic cells. Together with LPS-Binding Protein (LBP), CD14 binds to and mediates the innate immune response to bacterial lipopolysaccharide (LPS).
Ā
Recent Citations:
McMurray JL, von Borstel A, Taher TE, Syrimi E, Taylor GS, Sharif M, Rossjohn J, Remmerswaal EBM, Bemelman FJ, Vieira Braga FA, Chen X, Teichmann SA, Mohammed F, Berry AA, Lyke KE, Williamson KC, Stubbington MJT, Davey MS, Willcox CR, Willcox BE. Transcriptional profiling of human VĪ“1 TĀ cells reveals a pathogen-driven adaptive differentiation program. Cell Rep. 2022 May 24;39(8):110858. doi: 10.1016/j.celrep.2022.110858. PMID: 35613583.
| Name | APC Anti-Human CD14 (61D3) |
|---|---|
| Cat. No. | 20-0149 |
| Alternative Names | LPS-R, Mo2 |
| Gene ID | 929 |
| Clone | 61D3 |
| Isotype | Mouse IgG1, kappa |
| Reactivity | Human |
| Format | APC |
| Application | Flow Cytometry |
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Description
The 61D3 antibody is specific for human CD14, a 53-55 kDa GPI-anchored glycoprotein. CD14 is highly expressed on monocytes and to a lesser extent on interfollicular macrophages, and some dendritic cells. Together with LPS-Binding Protein (LBP), CD14 binds to and mediates the innate immune response to bacterial lipopolysaccharide (LPS).
Ā
Recent Citations:
McMurray JL, von Borstel A, Taher TE, Syrimi E, Taylor GS, Sharif M, Rossjohn J, Remmerswaal EBM, Bemelman FJ, Vieira Braga FA, Chen X, Teichmann SA, Mohammed F, Berry AA, Lyke KE, Williamson KC, Stubbington MJT, Davey MS, Willcox CR, Willcox BE. Transcriptional profiling of human VĪ“1 TĀ cells reveals a pathogen-driven adaptive differentiation program. Cell Rep. 2022 May 24;39(8):110858. doi: 10.1016/j.celrep.2022.110858. PMID: 35613583.
| Name | APC Anti-Human CD14 (61D3) |
|---|---|
| Cat. No. | 20-0149 |
| Alternative Names | LPS-R, Mo2 |
| Gene ID | 929 |
| Clone | 61D3 |
| Isotype | Mouse IgG1, kappa |
| Reactivity | Human |
| Format | APC |
| Application | Flow Cytometry |
