PE Anti-Mouse CD62L (L-Selectin) (MEL-14)
The MEL-14 antibody is specific for mouse CD62L, also known as L-Selectin, a cell adhesion molecule which facilitates lymphocyte ârollingâ on activated vascular endothelium and homing to high endothelial venules (HEV) as immune cells transmigrate from blood into peripheral tissues. L-Selectin is a member of a family of Selectin molecules which act together with the integrin αfamily of adhesion molecules to mediate leukocyte-endothelial interactions. L-Selectin is characteristically expressed by neutrophils, and is also found on B cells, monocytes, granulocytes, and at varying levels on naive, effector and memory T cells. It is rapidly shed upon cell activation, releasing into the circulation a soluble form whose biological role is of particular interest in cancer biology research.
The MEL-14 antibody may be used as a phenotypic marker for CD62L expression on a variety of immune cell types. Please note that CD62L (L-Selectin) itself is also referred to as MEL-14 in the literature.
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Recent Citations:
Sin JH, Kashyap S, Acenas D, Cortez JT, Lee J, Marson A, Matloubian M, Waterfield MR. ATF7ip Targets Transposable Elements for H3K9me3 Deposition to Modify CD8+Â T Cell Effector and Memory Responses. J Immunol. 2022 Feb 2:ji2100996. doi: 10.4049/jimmunol.2100996. Epub ahead of print. PMID: 35110421
| Name | PE Anti-Mouse CD62L (L-Selectin) (MEL-14) |
|---|---|
| Cat. No. | 50-0621 |
| Alternative Names | LECAM-1, Ly-22 |
| Gene ID | 20343 |
| Clone | MEL-14 |
| Isotype | Rat IgG2a, Îș |
| Reactivity | Mouse |
| Format | PE |
| Application | Flow Cytometry |
Original: $47.00
-70%$47.00
$14.10PE Anti-Mouse CD62L (L-Selectin) (MEL-14)
The MEL-14 antibody is specific for mouse CD62L, also known as L-Selectin, a cell adhesion molecule which facilitates lymphocyte ârollingâ on activated vascular endothelium and homing to high endothelial venules (HEV) as immune cells transmigrate from blood into peripheral tissues. L-Selectin is a member of a family of Selectin molecules which act together with the integrin αfamily of adhesion molecules to mediate leukocyte-endothelial interactions. L-Selectin is characteristically expressed by neutrophils, and is also found on B cells, monocytes, granulocytes, and at varying levels on naive, effector and memory T cells. It is rapidly shed upon cell activation, releasing into the circulation a soluble form whose biological role is of particular interest in cancer biology research.
The MEL-14 antibody may be used as a phenotypic marker for CD62L expression on a variety of immune cell types. Please note that CD62L (L-Selectin) itself is also referred to as MEL-14 in the literature.
Â
Recent Citations:
Sin JH, Kashyap S, Acenas D, Cortez JT, Lee J, Marson A, Matloubian M, Waterfield MR. ATF7ip Targets Transposable Elements for H3K9me3 Deposition to Modify CD8+Â T Cell Effector and Memory Responses. J Immunol. 2022 Feb 2:ji2100996. doi: 10.4049/jimmunol.2100996. Epub ahead of print. PMID: 35110421
| Name | PE Anti-Mouse CD62L (L-Selectin) (MEL-14) |
|---|---|
| Cat. No. | 50-0621 |
| Alternative Names | LECAM-1, Ly-22 |
| Gene ID | 20343 |
| Clone | MEL-14 |
| Isotype | Rat IgG2a, Îș |
| Reactivity | Mouse |
| Format | PE |
| Application | Flow Cytometry |
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Description
The MEL-14 antibody is specific for mouse CD62L, also known as L-Selectin, a cell adhesion molecule which facilitates lymphocyte ârollingâ on activated vascular endothelium and homing to high endothelial venules (HEV) as immune cells transmigrate from blood into peripheral tissues. L-Selectin is a member of a family of Selectin molecules which act together with the integrin αfamily of adhesion molecules to mediate leukocyte-endothelial interactions. L-Selectin is characteristically expressed by neutrophils, and is also found on B cells, monocytes, granulocytes, and at varying levels on naive, effector and memory T cells. It is rapidly shed upon cell activation, releasing into the circulation a soluble form whose biological role is of particular interest in cancer biology research.
The MEL-14 antibody may be used as a phenotypic marker for CD62L expression on a variety of immune cell types. Please note that CD62L (L-Selectin) itself is also referred to as MEL-14 in the literature.
Â
Recent Citations:
Sin JH, Kashyap S, Acenas D, Cortez JT, Lee J, Marson A, Matloubian M, Waterfield MR. ATF7ip Targets Transposable Elements for H3K9me3 Deposition to Modify CD8+Â T Cell Effector and Memory Responses. J Immunol. 2022 Feb 2:ji2100996. doi: 10.4049/jimmunol.2100996. Epub ahead of print. PMID: 35110421
| Name | PE Anti-Mouse CD62L (L-Selectin) (MEL-14) |
|---|---|
| Cat. No. | 50-0621 |
| Alternative Names | LECAM-1, Ly-22 |
| Gene ID | 20343 |
| Clone | MEL-14 |
| Isotype | Rat IgG2a, Îș |
| Reactivity | Mouse |
| Format | PE |
| Application | Flow Cytometry |
