PE Anti-Human CD54 (ICAM-1) (15.2)
The 15.2 antibody reacts with human CD54, also known as ICAM-1 (Intercellular Adhesion Molecule 1), a 90-110 kDa cell surface glycoprotein that is inducibly expressed on both immune and endothelial cells. As its name implies, ICAM-1 participates in cell-cell adhesion between ≥ ≥ ≥ leukocytes and endothelial cells, facilitating leukocyte recruitment and transmigration at sites of inflammation. The ligands for ICAM-1 are also expressed on leukocyte and endothelial cells, and include Mac-1, fibrinogen, and a member of the integrin αprotein family, LFA-1 (CD11a).
The 15.2 antibody may be used for analysis of ICAM-1 expression in human cells and tissues, and is reported to be cross-reactive with porcine ICAM-1.
| Name | PE Anti-Human CD54 (ICAM-1) (15.2) |
|---|---|
| Cat. No. | 50-0549 |
| Alternative Names | Intercellular adhesion molecule-1, ICAM1 |
| Gene ID | 3383 |
| Clone | 15.2 |
| Isotype | Mouse IgG1 |
| Reactivity | Human |
| Cross Reactivity | Pig |
| Format | PE |
| Application | Flow Cytometry |
PE Anti-Human CD54 (ICAM-1) (15.2)
The 15.2 antibody reacts with human CD54, also known as ICAM-1 (Intercellular Adhesion Molecule 1), a 90-110 kDa cell surface glycoprotein that is inducibly expressed on both immune and endothelial cells. As its name implies, ICAM-1 participates in cell-cell adhesion between ≥ ≥ ≥ leukocytes and endothelial cells, facilitating leukocyte recruitment and transmigration at sites of inflammation. The ligands for ICAM-1 are also expressed on leukocyte and endothelial cells, and include Mac-1, fibrinogen, and a member of the integrin αprotein family, LFA-1 (CD11a).
The 15.2 antibody may be used for analysis of ICAM-1 expression in human cells and tissues, and is reported to be cross-reactive with porcine ICAM-1.
| Name | PE Anti-Human CD54 (ICAM-1) (15.2) |
|---|---|
| Cat. No. | 50-0549 |
| Alternative Names | Intercellular adhesion molecule-1, ICAM1 |
| Gene ID | 3383 |
| Clone | 15.2 |
| Isotype | Mouse IgG1 |
| Reactivity | Human |
| Cross Reactivity | Pig |
| Format | PE |
| Application | Flow Cytometry |
Product Information
Product Information
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Description
The 15.2 antibody reacts with human CD54, also known as ICAM-1 (Intercellular Adhesion Molecule 1), a 90-110 kDa cell surface glycoprotein that is inducibly expressed on both immune and endothelial cells. As its name implies, ICAM-1 participates in cell-cell adhesion between ≥ ≥ ≥ leukocytes and endothelial cells, facilitating leukocyte recruitment and transmigration at sites of inflammation. The ligands for ICAM-1 are also expressed on leukocyte and endothelial cells, and include Mac-1, fibrinogen, and a member of the integrin αprotein family, LFA-1 (CD11a).
The 15.2 antibody may be used for analysis of ICAM-1 expression in human cells and tissues, and is reported to be cross-reactive with porcine ICAM-1.
| Name | PE Anti-Human CD54 (ICAM-1) (15.2) |
|---|---|
| Cat. No. | 50-0549 |
| Alternative Names | Intercellular adhesion molecule-1, ICAM1 |
| Gene ID | 3383 |
| Clone | 15.2 |
| Isotype | Mouse IgG1 |
| Reactivity | Human |
| Cross Reactivity | Pig |
| Format | PE |
| Application | Flow Cytometry |
