PE Anti-Human CD38 (HB7)
The HB7 antibody is specific for human CD38, a 45 kDa type II transmembrane glycoprotein expressed on thymocytes, plasma cells, and monocytes as well as other non-hematopoietic cells. T and B lymphocyte expression is discontinuous and varies based on differentiation state – present on immature cells, low on intermediate stages, and high on activated mature cells. It is found on most CD34+ cells, but not on pluripotent stem cells. CD38 is an ectoenzyme that functions to catalyze the synthesis and hydrolysis of cyclic ADP-ribose and is involved in cell signaling, regulating cell adhesion, and activation. Additionally, CD38 has been shown to be a prognostic marker for some leukemias and other diseases.
| Name | PE Anti-Human CD38 (HB7) |
|---|---|
| Cat. No. | 50-0388 |
| Alternative Names | T10, ADP-ribosyl cyclase, cyclic ADP ribose hydrolase |
| Gene ID | 952 |
| Clone | HB7 |
| Isotype | Mouse IgG1, kappa |
| Reactivity | Human |
| Format | PE |
| Application | Flow Cytometry |
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PE Anti-Human CD38 (HB7)
The HB7 antibody is specific for human CD38, a 45 kDa type II transmembrane glycoprotein expressed on thymocytes, plasma cells, and monocytes as well as other non-hematopoietic cells. T and B lymphocyte expression is discontinuous and varies based on differentiation state – present on immature cells, low on intermediate stages, and high on activated mature cells. It is found on most CD34+ cells, but not on pluripotent stem cells. CD38 is an ectoenzyme that functions to catalyze the synthesis and hydrolysis of cyclic ADP-ribose and is involved in cell signaling, regulating cell adhesion, and activation. Additionally, CD38 has been shown to be a prognostic marker for some leukemias and other diseases.
| Name | PE Anti-Human CD38 (HB7) |
|---|---|
| Cat. No. | 50-0388 |
| Alternative Names | T10, ADP-ribosyl cyclase, cyclic ADP ribose hydrolase |
| Gene ID | 952 |
| Clone | HB7 |
| Isotype | Mouse IgG1, kappa |
| Reactivity | Human |
| Format | PE |
| Application | Flow Cytometry |
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Product Information
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Description
The HB7 antibody is specific for human CD38, a 45 kDa type II transmembrane glycoprotein expressed on thymocytes, plasma cells, and monocytes as well as other non-hematopoietic cells. T and B lymphocyte expression is discontinuous and varies based on differentiation state – present on immature cells, low on intermediate stages, and high on activated mature cells. It is found on most CD34+ cells, but not on pluripotent stem cells. CD38 is an ectoenzyme that functions to catalyze the synthesis and hydrolysis of cyclic ADP-ribose and is involved in cell signaling, regulating cell adhesion, and activation. Additionally, CD38 has been shown to be a prognostic marker for some leukemias and other diseases.
| Name | PE Anti-Human CD38 (HB7) |
|---|---|
| Cat. No. | 50-0388 |
| Alternative Names | T10, ADP-ribosyl cyclase, cyclic ADP ribose hydrolase |
| Gene ID | 952 |
| Clone | HB7 |
| Isotype | Mouse IgG1, kappa |
| Reactivity | Human |
| Format | PE |
| Application | Flow Cytometry |
