APC-Cyanine7 Anti-Mouse CD45.1 (A20)
The A20 antibody reacts with mouse CD45.1, also known as Ly5.1, which is a strain-specific allelic form of the CD45 Leukocyte Common Antigen (LCA). Functionally, CD45 is a protein tyrosine phosphatase whose broad cell distribution supports a critical role in many leukocyte functions, including regulation of signal transduction and cell activation associated with the T cell and B cell receptors.
The A20 antibody is typically used as a leukocyte marker in Ly5.1 mouse strains: SJL/J, DA, STS/A and RIII. The antibody has been demonstrated to specific for CD45.1 and is not cross-reactive with CD45.2 bearing cells.
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Recent Publications:
Fu Z, Dean JW, Xiong L, et al. Mitochondrial transcription factor A in RORγt+ lymphocytes regulate small intestine homeostasis and metabolism. Nat Commun. 2021 Jul 22;12(1):4462. doi: 10.1038/s41467-021-24755-9. PMID: 34294718.
» View on Nature Communications
Baba T, Yoshida T, Tanabe Y, et al. Cytoplasmic DNA accumulation preferentially triggers cell death of myeloid leukemia cells by interacting with intracellular DNA sensing pathway. Cell Death Dis. 2021 Mar 26;12(4):322. doi: 10.1038/s41419-021-03587-x. PMID: 33771977. Â
| Name | APC-Cyanine7 Anti-Mouse CD45.1 (A20) |
|---|---|
| Cat. No. | 25-0453 |
| Alternative Names | 25-0453, SJL, Ly5.1 |
| Gene ID | 19264 |
| Clone | A20 |
| Isotype | Mouse IgG2a, κ |
| Reactivity | Mouse |
| Format | APC-Cyanine7 |
| Application | Flow Cytometry |
Original: $77.00
-70%$77.00
$23.10APC-Cyanine7 Anti-Mouse CD45.1 (A20)
The A20 antibody reacts with mouse CD45.1, also known as Ly5.1, which is a strain-specific allelic form of the CD45 Leukocyte Common Antigen (LCA). Functionally, CD45 is a protein tyrosine phosphatase whose broad cell distribution supports a critical role in many leukocyte functions, including regulation of signal transduction and cell activation associated with the T cell and B cell receptors.
The A20 antibody is typically used as a leukocyte marker in Ly5.1 mouse strains: SJL/J, DA, STS/A and RIII. The antibody has been demonstrated to specific for CD45.1 and is not cross-reactive with CD45.2 bearing cells.
Â
Recent Publications:
Fu Z, Dean JW, Xiong L, et al. Mitochondrial transcription factor A in RORγt+ lymphocytes regulate small intestine homeostasis and metabolism. Nat Commun. 2021 Jul 22;12(1):4462. doi: 10.1038/s41467-021-24755-9. PMID: 34294718.
» View on Nature Communications
Baba T, Yoshida T, Tanabe Y, et al. Cytoplasmic DNA accumulation preferentially triggers cell death of myeloid leukemia cells by interacting with intracellular DNA sensing pathway. Cell Death Dis. 2021 Mar 26;12(4):322. doi: 10.1038/s41419-021-03587-x. PMID: 33771977. Â
| Name | APC-Cyanine7 Anti-Mouse CD45.1 (A20) |
|---|---|
| Cat. No. | 25-0453 |
| Alternative Names | 25-0453, SJL, Ly5.1 |
| Gene ID | 19264 |
| Clone | A20 |
| Isotype | Mouse IgG2a, κ |
| Reactivity | Mouse |
| Format | APC-Cyanine7 |
| Application | Flow Cytometry |
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Description
The A20 antibody reacts with mouse CD45.1, also known as Ly5.1, which is a strain-specific allelic form of the CD45 Leukocyte Common Antigen (LCA). Functionally, CD45 is a protein tyrosine phosphatase whose broad cell distribution supports a critical role in many leukocyte functions, including regulation of signal transduction and cell activation associated with the T cell and B cell receptors.
The A20 antibody is typically used as a leukocyte marker in Ly5.1 mouse strains: SJL/J, DA, STS/A and RIII. The antibody has been demonstrated to specific for CD45.1 and is not cross-reactive with CD45.2 bearing cells.
Â
Recent Publications:
Fu Z, Dean JW, Xiong L, et al. Mitochondrial transcription factor A in RORγt+ lymphocytes regulate small intestine homeostasis and metabolism. Nat Commun. 2021 Jul 22;12(1):4462. doi: 10.1038/s41467-021-24755-9. PMID: 34294718.
» View on Nature Communications
Baba T, Yoshida T, Tanabe Y, et al. Cytoplasmic DNA accumulation preferentially triggers cell death of myeloid leukemia cells by interacting with intracellular DNA sensing pathway. Cell Death Dis. 2021 Mar 26;12(4):322. doi: 10.1038/s41419-021-03587-x. PMID: 33771977. Â
| Name | APC-Cyanine7 Anti-Mouse CD45.1 (A20) |
|---|---|
| Cat. No. | 25-0453 |
| Alternative Names | 25-0453, SJL, Ly5.1 |
| Gene ID | 19264 |
| Clone | A20 |
| Isotype | Mouse IgG2a, κ |
| Reactivity | Mouse |
| Format | APC-Cyanine7 |
| Application | Flow Cytometry |
