APC Anti-Mouse CD69 (H1.2F3)
The H1.2F3 antibody reacts with mouse CD69, a type II transmembrane glycoprotein also known as the Very Early Activation Antigen, EA-1, Leu23, Activation Inducer Molecule (AIM) and CLEC2C. CD69 is expressed as a 60 kDa disulfide-linked homodimer on activated T and B cells, NK cells, neutrophils and monocytes. Induction occurs rapidly upon activation. It is also constitutively expressed on platelets and a subset of thymocytes. CD69 acts as a co-stimulatory molecule involved in activation and proliferation of T cells, and may be a marker for thymocytes undergoing TCR-mediated positive selection.
Co-stimulation with the H1.2F3 clone has been reported to enhance T cell and macrophage activation. Please choose the appropriate format for each application.
| Name | APC Anti-Mouse CD69 (H1.2F3) |
|---|---|
| Cat. No. | 20-0691 |
| Alternative Names | Very Early Activation Antigen (VEA), AIM, EA1, MLR3, gp34/28 |
| Gene ID | 12515 |
| Clone | H1.2F3 |
| Isotype | Armenian Hamster IgG |
| Reactivity | Mouse |
| Format | APC |
| Application | Flow Cytometry |
APC Anti-Mouse CD69 (H1.2F3)
The H1.2F3 antibody reacts with mouse CD69, a type II transmembrane glycoprotein also known as the Very Early Activation Antigen, EA-1, Leu23, Activation Inducer Molecule (AIM) and CLEC2C. CD69 is expressed as a 60 kDa disulfide-linked homodimer on activated T and B cells, NK cells, neutrophils and monocytes. Induction occurs rapidly upon activation. It is also constitutively expressed on platelets and a subset of thymocytes. CD69 acts as a co-stimulatory molecule involved in activation and proliferation of T cells, and may be a marker for thymocytes undergoing TCR-mediated positive selection.
Co-stimulation with the H1.2F3 clone has been reported to enhance T cell and macrophage activation. Please choose the appropriate format for each application.
| Name | APC Anti-Mouse CD69 (H1.2F3) |
|---|---|
| Cat. No. | 20-0691 |
| Alternative Names | Very Early Activation Antigen (VEA), AIM, EA1, MLR3, gp34/28 |
| Gene ID | 12515 |
| Clone | H1.2F3 |
| Isotype | Armenian Hamster IgG |
| Reactivity | Mouse |
| Format | APC |
| Application | Flow Cytometry |
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Product Information
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Description
The H1.2F3 antibody reacts with mouse CD69, a type II transmembrane glycoprotein also known as the Very Early Activation Antigen, EA-1, Leu23, Activation Inducer Molecule (AIM) and CLEC2C. CD69 is expressed as a 60 kDa disulfide-linked homodimer on activated T and B cells, NK cells, neutrophils and monocytes. Induction occurs rapidly upon activation. It is also constitutively expressed on platelets and a subset of thymocytes. CD69 acts as a co-stimulatory molecule involved in activation and proliferation of T cells, and may be a marker for thymocytes undergoing TCR-mediated positive selection.
Co-stimulation with the H1.2F3 clone has been reported to enhance T cell and macrophage activation. Please choose the appropriate format for each application.
| Name | APC Anti-Mouse CD69 (H1.2F3) |
|---|---|
| Cat. No. | 20-0691 |
| Alternative Names | Very Early Activation Antigen (VEA), AIM, EA1, MLR3, gp34/28 |
| Gene ID | 12515 |
| Clone | H1.2F3 |
| Isotype | Armenian Hamster IgG |
| Reactivity | Mouse |
| Format | APC |
| Application | Flow Cytometry |
