APC Anti-Mouse CD45 (30-F11)
The 30-F11 antibody reacts with mouse CD45, which is one of the most abundant hematopoietic markers and is expressed on all leukocytes (the Leukocyte Common Antigen, LCA). CD45 is a protein tyrosine phosphatase existing in several isoforms, each being generated and expressed in cell-specific patterns. With its broad cell distribution, CD45 is critical for many leukocyte functions, regulating signal transduction and cell activation associated with the T cell receptor, B cell receptor, and IL-2 receptor. Other forms of CD45, with restricted cellular expression, include CD45R (B220), CD45RA, CD45RB, CD45RO and others.
The 30-F11 antibody is widely used as a leukocyte marker for B cells, T cell subsets and NK cell subsets.
Recent Publications:
Marsh SE, Abud EM, Lakatos A, Karimzadeh A, Yeung ST, Davtyan H, Fote GM, Lau L, Weinger JG, Lane TE, Inlay MA, Poon WW and Blurton-Jones M. 2016.Proc Natl Acad Sci USA. doi: 10.1073/pnas.1525466113. (Flow Cytometry)
| Name | APC Anti-Mouse CD45 (30-F11) |
|---|---|
| Cat. No. | 20-0451 |
| Alternative Names | Leukocyte Common Antigen, LCA, Ly-5 |
| Gene ID | 19264 |
| Clone | 30-F11 |
| Isotype | Rat IgG2b, κ |
| Reactivity | Mouse |
| Format | APC |
| Application | Flow Cytometry |
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APC Anti-Mouse CD45 (30-F11)
The 30-F11 antibody reacts with mouse CD45, which is one of the most abundant hematopoietic markers and is expressed on all leukocytes (the Leukocyte Common Antigen, LCA). CD45 is a protein tyrosine phosphatase existing in several isoforms, each being generated and expressed in cell-specific patterns. With its broad cell distribution, CD45 is critical for many leukocyte functions, regulating signal transduction and cell activation associated with the T cell receptor, B cell receptor, and IL-2 receptor. Other forms of CD45, with restricted cellular expression, include CD45R (B220), CD45RA, CD45RB, CD45RO and others.
The 30-F11 antibody is widely used as a leukocyte marker for B cells, T cell subsets and NK cell subsets.
Recent Publications:
Marsh SE, Abud EM, Lakatos A, Karimzadeh A, Yeung ST, Davtyan H, Fote GM, Lau L, Weinger JG, Lane TE, Inlay MA, Poon WW and Blurton-Jones M. 2016.Proc Natl Acad Sci USA. doi: 10.1073/pnas.1525466113. (Flow Cytometry)
| Name | APC Anti-Mouse CD45 (30-F11) |
|---|---|
| Cat. No. | 20-0451 |
| Alternative Names | Leukocyte Common Antigen, LCA, Ly-5 |
| Gene ID | 19264 |
| Clone | 30-F11 |
| Isotype | Rat IgG2b, κ |
| Reactivity | Mouse |
| Format | APC |
| Application | Flow Cytometry |
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Description
The 30-F11 antibody reacts with mouse CD45, which is one of the most abundant hematopoietic markers and is expressed on all leukocytes (the Leukocyte Common Antigen, LCA). CD45 is a protein tyrosine phosphatase existing in several isoforms, each being generated and expressed in cell-specific patterns. With its broad cell distribution, CD45 is critical for many leukocyte functions, regulating signal transduction and cell activation associated with the T cell receptor, B cell receptor, and IL-2 receptor. Other forms of CD45, with restricted cellular expression, include CD45R (B220), CD45RA, CD45RB, CD45RO and others.
The 30-F11 antibody is widely used as a leukocyte marker for B cells, T cell subsets and NK cell subsets.
Recent Publications:
Marsh SE, Abud EM, Lakatos A, Karimzadeh A, Yeung ST, Davtyan H, Fote GM, Lau L, Weinger JG, Lane TE, Inlay MA, Poon WW and Blurton-Jones M. 2016.Proc Natl Acad Sci USA. doi: 10.1073/pnas.1525466113. (Flow Cytometry)
| Name | APC Anti-Mouse CD45 (30-F11) |
|---|---|
| Cat. No. | 20-0451 |
| Alternative Names | Leukocyte Common Antigen, LCA, Ly-5 |
| Gene ID | 19264 |
| Clone | 30-F11 |
| Isotype | Rat IgG2b, κ |
| Reactivity | Mouse |
| Format | APC |
| Application | Flow Cytometry |
