APC Anti-Human CD23 (EBVCS-5)
The EBVCS-5 antibody is specific for human CD23, also known as the low affinity IgE receptor (FceRII), a 45 kDa type II transmembrane protein and member of the immunoglobulin superfamily. It is expressed on most B cells and is upregulated upon activation. It is also present on mantle zone B cells, eosinophils, monocytes and a subset of T cells and platelets. CD23 plays a role in B cell development and differentiation, and also functions to regulate IgE production. Soluble secreted forms of CD23 have been reported to bind IgE, stimulate release of pro-inflammatory cytokines from monocytes, and play a role in B cell differentiation.
| Name | APC Anti-Human CD23 (EBVCS-5) |
|---|---|
| Cat. No. | 20-0237 |
| Alternative Names | FcER2, Fc?RII, Low affinity immunoglobulin epsilon Fc receptor, BLAST-2, Leu-20, B6 |
| Gene ID | 2208 |
| Clone | EBVCS-5 |
| Isotype | Mouse IgG1, kappa |
| Reactivity | Human |
| Format | APC |
| Application | Flow Cytometry |
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APC Anti-Human CD23 (EBVCS-5)
The EBVCS-5 antibody is specific for human CD23, also known as the low affinity IgE receptor (FceRII), a 45 kDa type II transmembrane protein and member of the immunoglobulin superfamily. It is expressed on most B cells and is upregulated upon activation. It is also present on mantle zone B cells, eosinophils, monocytes and a subset of T cells and platelets. CD23 plays a role in B cell development and differentiation, and also functions to regulate IgE production. Soluble secreted forms of CD23 have been reported to bind IgE, stimulate release of pro-inflammatory cytokines from monocytes, and play a role in B cell differentiation.
| Name | APC Anti-Human CD23 (EBVCS-5) |
|---|---|
| Cat. No. | 20-0237 |
| Alternative Names | FcER2, Fc?RII, Low affinity immunoglobulin epsilon Fc receptor, BLAST-2, Leu-20, B6 |
| Gene ID | 2208 |
| Clone | EBVCS-5 |
| Isotype | Mouse IgG1, kappa |
| Reactivity | Human |
| Format | APC |
| Application | Flow Cytometry |
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Description
The EBVCS-5 antibody is specific for human CD23, also known as the low affinity IgE receptor (FceRII), a 45 kDa type II transmembrane protein and member of the immunoglobulin superfamily. It is expressed on most B cells and is upregulated upon activation. It is also present on mantle zone B cells, eosinophils, monocytes and a subset of T cells and platelets. CD23 plays a role in B cell development and differentiation, and also functions to regulate IgE production. Soluble secreted forms of CD23 have been reported to bind IgE, stimulate release of pro-inflammatory cytokines from monocytes, and play a role in B cell differentiation.
| Name | APC Anti-Human CD23 (EBVCS-5) |
|---|---|
| Cat. No. | 20-0237 |
| Alternative Names | FcER2, Fc?RII, Low affinity immunoglobulin epsilon Fc receptor, BLAST-2, Leu-20, B6 |
| Gene ID | 2208 |
| Clone | EBVCS-5 |
| Isotype | Mouse IgG1, kappa |
| Reactivity | Human |
| Format | APC |
| Application | Flow Cytometry |
