PE/Cyanine7 anti-mouse Integrin αVβ6
Integrins are heterodimeric transmembrane receptors that mediate cell-cell and cell-extracellular matrix adhesion. Integrin β6 associates exclusively with the αV subunit forming an αVβ6 complex that is expressed specifically on epithelial cells. Integrin αVβ6 is a receptor for multiple extracellular matrix (ECM) proteins, including tenascin, fibronectin, and vitronectin. It is also a receptor for the latency-associated peptide (LAP) of TGF-β and is involved in TGF-β activation. Its expression is upregulated during wound healing and in some cancers.
PRODUCT DETAILS
Clone: S20012E
Antibody Type: Monoclonal
Reactivity: Mouse
Format: Integrin alphaVbeta6
Host: Rat
Isotype: IgG2b, λ
Applications: FC - Quality tested
Regulatory Status: RUO
Note to Purchaser: This product is manufactured and supplied by BioLegend, Inc. under an agreement between BioLegend, Inc. and Cytek Biosciences, Inc. Information related to this product is provided by BioLegend, Inc.
Original: $196.00
-70%$196.00
$58.80PE/Cyanine7 anti-mouse Integrin αVβ6
Integrins are heterodimeric transmembrane receptors that mediate cell-cell and cell-extracellular matrix adhesion. Integrin β6 associates exclusively with the αV subunit forming an αVβ6 complex that is expressed specifically on epithelial cells. Integrin αVβ6 is a receptor for multiple extracellular matrix (ECM) proteins, including tenascin, fibronectin, and vitronectin. It is also a receptor for the latency-associated peptide (LAP) of TGF-β and is involved in TGF-β activation. Its expression is upregulated during wound healing and in some cancers.
PRODUCT DETAILS
Clone: S20012E
Antibody Type: Monoclonal
Reactivity: Mouse
Format: Integrin alphaVbeta6
Host: Rat
Isotype: IgG2b, λ
Applications: FC - Quality tested
Regulatory Status: RUO
Note to Purchaser: This product is manufactured and supplied by BioLegend, Inc. under an agreement between BioLegend, Inc. and Cytek Biosciences, Inc. Information related to this product is provided by BioLegend, Inc.
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Description
Integrins are heterodimeric transmembrane receptors that mediate cell-cell and cell-extracellular matrix adhesion. Integrin β6 associates exclusively with the αV subunit forming an αVβ6 complex that is expressed specifically on epithelial cells. Integrin αVβ6 is a receptor for multiple extracellular matrix (ECM) proteins, including tenascin, fibronectin, and vitronectin. It is also a receptor for the latency-associated peptide (LAP) of TGF-β and is involved in TGF-β activation. Its expression is upregulated during wound healing and in some cancers.
PRODUCT DETAILS
Clone: S20012E
Antibody Type: Monoclonal
Reactivity: Mouse
Format: Integrin alphaVbeta6
Host: Rat
Isotype: IgG2b, λ
Applications: FC - Quality tested
Regulatory Status: RUO
Note to Purchaser: This product is manufactured and supplied by BioLegend, Inc. under an agreement between BioLegend, Inc. and Cytek Biosciences, Inc. Information related to this product is provided by BioLegend, Inc.
