PE anti-mouse CD369 (Dectin-1, CLEC7A)
CD369 (Dectin-1), also known as CLEC7A, is a 43 kD type II transmembrane protein. The extracellular portion of Dectin-1 contains one C-type lectin domain, and its cytoplasmic tail has one immunoreceptor tyrosine-based activation motif (ITAM). Dectin-1 binds β-1,3-linked and β-1,6-glucans (abundant in the cell wall of fungi and yeast), mediates phagocytosis, and induces cytokine production and oxidative burst. It is also involved in TLR2-mediated NF-kB activation. Dectin-1 is expressed by macrophages, neutrophils, dendritic, and Langerhans cells.
PRODUCT DETAILS
Clone: RH1
Antibody Type: Monoclonal
Reactivity: Mouse
Format: PE
Host: Rat
Isotype: IgG1, κ
Applications: FC - Quality tested
Regulatory Status: RUO
Note to Purchaser: This product is manufactured and supplied by BioLegend, Inc. under an agreement between BioLegend, Inc. and Cytek Biosciences, Inc. Information related to this product is provided by BioLegend, Inc.
Original: $128.00
-70%$128.00
$38.40PE anti-mouse CD369 (Dectin-1, CLEC7A)
CD369 (Dectin-1), also known as CLEC7A, is a 43 kD type II transmembrane protein. The extracellular portion of Dectin-1 contains one C-type lectin domain, and its cytoplasmic tail has one immunoreceptor tyrosine-based activation motif (ITAM). Dectin-1 binds β-1,3-linked and β-1,6-glucans (abundant in the cell wall of fungi and yeast), mediates phagocytosis, and induces cytokine production and oxidative burst. It is also involved in TLR2-mediated NF-kB activation. Dectin-1 is expressed by macrophages, neutrophils, dendritic, and Langerhans cells.
PRODUCT DETAILS
Clone: RH1
Antibody Type: Monoclonal
Reactivity: Mouse
Format: PE
Host: Rat
Isotype: IgG1, κ
Applications: FC - Quality tested
Regulatory Status: RUO
Note to Purchaser: This product is manufactured and supplied by BioLegend, Inc. under an agreement between BioLegend, Inc. and Cytek Biosciences, Inc. Information related to this product is provided by BioLegend, Inc.
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Description
CD369 (Dectin-1), also known as CLEC7A, is a 43 kD type II transmembrane protein. The extracellular portion of Dectin-1 contains one C-type lectin domain, and its cytoplasmic tail has one immunoreceptor tyrosine-based activation motif (ITAM). Dectin-1 binds β-1,3-linked and β-1,6-glucans (abundant in the cell wall of fungi and yeast), mediates phagocytosis, and induces cytokine production and oxidative burst. It is also involved in TLR2-mediated NF-kB activation. Dectin-1 is expressed by macrophages, neutrophils, dendritic, and Langerhans cells.
PRODUCT DETAILS
Clone: RH1
Antibody Type: Monoclonal
Reactivity: Mouse
Format: PE
Host: Rat
Isotype: IgG1, κ
Applications: FC - Quality tested
Regulatory Status: RUO
Note to Purchaser: This product is manufactured and supplied by BioLegend, Inc. under an agreement between BioLegend, Inc. and Cytek Biosciences, Inc. Information related to this product is provided by BioLegend, Inc.
