PE anti-human CD262 (DR5, TRAIL-R2)
DR5, also known as TRAIL-R2, TRICK2, KILLER, and CD262, is 55 kD member 10B of the TNF receptor superfamily (TNFRSF10B). It binds the cytotoxic ligand, TRAIL, and induces apoptosis. The DR5 receptor is broadly expressed on a variety of normal tissues and many tumors. DR5 expression has been reported to be upregulated in human cells by interferon-α, 2-methoxyestradiol, and paclitaxel, and downregulated by adenoviral E3 proteins.
PRODUCT DETAILS
Clone: A21121I
Antibody Type: Monoclonal
Reactivity: Human
Format: CD262
Host: Mouse
Isotype: IgG2a, κ
Applications: FC - Quality tested
Regulatory Status: RUO
Note to Purchaser: This product is manufactured and supplied by BioLegend, Inc. under an agreement between BioLegend, Inc. and Cytek Biosciences, Inc. Information related to this product is provided by BioLegend, Inc.
PE anti-human CD262 (DR5, TRAIL-R2)
DR5, also known as TRAIL-R2, TRICK2, KILLER, and CD262, is 55 kD member 10B of the TNF receptor superfamily (TNFRSF10B). It binds the cytotoxic ligand, TRAIL, and induces apoptosis. The DR5 receptor is broadly expressed on a variety of normal tissues and many tumors. DR5 expression has been reported to be upregulated in human cells by interferon-α, 2-methoxyestradiol, and paclitaxel, and downregulated by adenoviral E3 proteins.
PRODUCT DETAILS
Clone: A21121I
Antibody Type: Monoclonal
Reactivity: Human
Format: CD262
Host: Mouse
Isotype: IgG2a, κ
Applications: FC - Quality tested
Regulatory Status: RUO
Note to Purchaser: This product is manufactured and supplied by BioLegend, Inc. under an agreement between BioLegend, Inc. and Cytek Biosciences, Inc. Information related to this product is provided by BioLegend, Inc.
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Product Information
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Description
DR5, also known as TRAIL-R2, TRICK2, KILLER, and CD262, is 55 kD member 10B of the TNF receptor superfamily (TNFRSF10B). It binds the cytotoxic ligand, TRAIL, and induces apoptosis. The DR5 receptor is broadly expressed on a variety of normal tissues and many tumors. DR5 expression has been reported to be upregulated in human cells by interferon-α, 2-methoxyestradiol, and paclitaxel, and downregulated by adenoviral E3 proteins.
PRODUCT DETAILS
Clone: A21121I
Antibody Type: Monoclonal
Reactivity: Human
Format: CD262
Host: Mouse
Isotype: IgG2a, κ
Applications: FC - Quality tested
Regulatory Status: RUO
Note to Purchaser: This product is manufactured and supplied by BioLegend, Inc. under an agreement between BioLegend, Inc. and Cytek Biosciences, Inc. Information related to this product is provided by BioLegend, Inc.
