For Research Use Only. Not intended for use in diagnostic procedures.
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In Vivo Ready™ Anti-Mouse CD40 (FGK45)
The FGK45 antibody reacts with mouse CD40, a 40-50 kDa glycoprotein member of the tumor necrosis factor receptor (TNFR) family. CD40 is constitutively expressed by antigen presenting cells, including dendritic cells, B cells, and macrophages. The interaction of CD40 and its ligand CD154, expressed on activated T cells, plays an essential role in mediating a broad range of immune and inflammatory responses including T cell dependent immunoglobulin class switching, germinal center formation, and the development of memory B cells.
The FGK45 clone is reported to be functionally useful for both in vitro and in vivo activation of CD40 expressing antigen presenting cells.
| Name | In Vivo Ready™ Anti-Mouse CD40 (FGK45) |
|---|---|
| Cat. No. | 40-8050 |
| Data Sheets | TDS | SDS |
| Alternative Names | Bp50, gp39, HIGM1, IGM, IMD3, T-BAM, TRAP, TNFRSF5, p50, FGK4.5 |
| Gene ID | 21939 |
| Clone | FGK45 |
| Isotype | Rat IgG2a |
| Reactivity | Mouse |
| Format | In Vivo Ready™ |
| Application | FC - Validated FA - Reported in literature, not validated in house |
For Research Use Only. Not intended for use in diagnostic procedures.
In Vivo Ready™ Anti-Mouse CD40 (FGK45)
The FGK45 antibody reacts with mouse CD40, a 40-50 kDa glycoprotein member of the tumor necrosis factor receptor (TNFR) family. CD40 is constitutively expressed by antigen presenting cells, including dendritic cells, B cells, and macrophages. The interaction of CD40 and its ligand CD154, expressed on activated T cells, plays an essential role in mediating a broad range of immune and inflammatory responses including T cell dependent immunoglobulin class switching, germinal center formation, and the development of memory B cells.
The FGK45 clone is reported to be functionally useful for both in vitro and in vivo activation of CD40 expressing antigen presenting cells.
| Name | In Vivo Ready™ Anti-Mouse CD40 (FGK45) |
|---|---|
| Cat. No. | 40-8050 |
| Data Sheets | TDS | SDS |
| Alternative Names | Bp50, gp39, HIGM1, IGM, IMD3, T-BAM, TRAP, TNFRSF5, p50, FGK4.5 |
| Gene ID | 21939 |
| Clone | FGK45 |
| Isotype | Rat IgG2a |
| Reactivity | Mouse |
| Format | In Vivo Ready™ |
| Application | FC - Validated FA - Reported in literature, not validated in house |
For Research Use Only. Not intended for use in diagnostic procedures.
Product Information
Product Information
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Description
The FGK45 antibody reacts with mouse CD40, a 40-50 kDa glycoprotein member of the tumor necrosis factor receptor (TNFR) family. CD40 is constitutively expressed by antigen presenting cells, including dendritic cells, B cells, and macrophages. The interaction of CD40 and its ligand CD154, expressed on activated T cells, plays an essential role in mediating a broad range of immune and inflammatory responses including T cell dependent immunoglobulin class switching, germinal center formation, and the development of memory B cells.
The FGK45 clone is reported to be functionally useful for both in vitro and in vivo activation of CD40 expressing antigen presenting cells.
| Name | In Vivo Ready™ Anti-Mouse CD40 (FGK45) |
|---|---|
| Cat. No. | 40-8050 |
| Data Sheets | TDS | SDS |
| Alternative Names | Bp50, gp39, HIGM1, IGM, IMD3, T-BAM, TRAP, TNFRSF5, p50, FGK4.5 |
| Gene ID | 21939 |
| Clone | FGK45 |
| Isotype | Rat IgG2a |
| Reactivity | Mouse |
| Format | In Vivo Ready™ |
| Application | FC - Validated FA - Reported in literature, not validated in house |
For Research Use Only. Not intended for use in diagnostic procedures.
