CD31 (PECAM-1) Monoclonal Antibody (Gi18), eBioscience
PRODUCT DETAILS
Host: Mouse
Isotype: IgG1
Clonality: Monoclonal
Clone: Gi18
Reactivity: Hu
Application: Flow Cytometry
Tested Dilution: Assay-Dependent
Concentration: 1 mg/mL
Storage: 4°C
Formulation: PBS with no preservative; pH 7.2-7.4
Purification: Affinity chromatography
Data Sheet: TDS
Specific Information
Description: The antibody BMS137 recognizes platelet endothelial cell adhesion molecule 1 (PECAM-1) also known as CD31, a transmembrane glycoprotein with a molecular weight of approximately 130 kDa, depending on the degree of glycosylation. PECAM-1 is constitutively expressed on all vascular cells and has provided a useful immunohistochemical marker of blood vessels, particularly in the setting of angiogenesis. It has also been found on platelets, monocytes, neutrophils and CD8+ T cells. Bone marrow stem cells and transformed cell lines of the myeloid and megakaryocytic lineage also express PECAM-1. Interestingly, PECAM-1 was also detected on human, mouse and rat solid tumor lines.
Recent studies suggest a role for PECAM-1 in the inflammatory process and leukocyte-endothelial interaction. PECAM-1 is an early and sensitive marker for tumor-induced angiogenesis. Several data have suggested that PECAM-1 may be involved in the process of angiogenesis in a developing vertebrate embryo as well as during metastases formation.
Applications Reported: This BMS137 antibody has been reported for use in ELISA, western blotting under non-reduced conditions, cell staining followed by both FACS and flow cytometric analysis, immunohistochemical staining of both frozen and FFPE tissues.
Applications Tested: This BMS137 antibody has been tested by western blot analysis and immunohistochemistry on human FFPE tissue using both low and high pH antigen retrieval at 30 µg/mL. It is recommended that the antibody be carefully titrated for optimal performance in the assay of interest.
Purity: >95%.
Â
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.Original: $273.00
-70%$273.00
$81.90CD31 (PECAM-1) Monoclonal Antibody (Gi18), eBioscience
PRODUCT DETAILS
Host: Mouse
Isotype: IgG1
Clonality: Monoclonal
Clone: Gi18
Reactivity: Hu
Application: Flow Cytometry
Tested Dilution: Assay-Dependent
Concentration: 1 mg/mL
Storage: 4°C
Formulation: PBS with no preservative; pH 7.2-7.4
Purification: Affinity chromatography
Data Sheet: TDS
Specific Information
Description: The antibody BMS137 recognizes platelet endothelial cell adhesion molecule 1 (PECAM-1) also known as CD31, a transmembrane glycoprotein with a molecular weight of approximately 130 kDa, depending on the degree of glycosylation. PECAM-1 is constitutively expressed on all vascular cells and has provided a useful immunohistochemical marker of blood vessels, particularly in the setting of angiogenesis. It has also been found on platelets, monocytes, neutrophils and CD8+ T cells. Bone marrow stem cells and transformed cell lines of the myeloid and megakaryocytic lineage also express PECAM-1. Interestingly, PECAM-1 was also detected on human, mouse and rat solid tumor lines.
Recent studies suggest a role for PECAM-1 in the inflammatory process and leukocyte-endothelial interaction. PECAM-1 is an early and sensitive marker for tumor-induced angiogenesis. Several data have suggested that PECAM-1 may be involved in the process of angiogenesis in a developing vertebrate embryo as well as during metastases formation.
Applications Reported: This BMS137 antibody has been reported for use in ELISA, western blotting under non-reduced conditions, cell staining followed by both FACS and flow cytometric analysis, immunohistochemical staining of both frozen and FFPE tissues.
Applications Tested: This BMS137 antibody has been tested by western blot analysis and immunohistochemistry on human FFPE tissue using both low and high pH antigen retrieval at 30 µg/mL. It is recommended that the antibody be carefully titrated for optimal performance in the assay of interest.
Purity: >95%.
Â
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.Product Information
Product Information
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Description
PRODUCT DETAILS
Host: Mouse
Isotype: IgG1
Clonality: Monoclonal
Clone: Gi18
Reactivity: Hu
Application: Flow Cytometry
Tested Dilution: Assay-Dependent
Concentration: 1 mg/mL
Storage: 4°C
Formulation: PBS with no preservative; pH 7.2-7.4
Purification: Affinity chromatography
Data Sheet: TDS
Specific Information
Description: The antibody BMS137 recognizes platelet endothelial cell adhesion molecule 1 (PECAM-1) also known as CD31, a transmembrane glycoprotein with a molecular weight of approximately 130 kDa, depending on the degree of glycosylation. PECAM-1 is constitutively expressed on all vascular cells and has provided a useful immunohistochemical marker of blood vessels, particularly in the setting of angiogenesis. It has also been found on platelets, monocytes, neutrophils and CD8+ T cells. Bone marrow stem cells and transformed cell lines of the myeloid and megakaryocytic lineage also express PECAM-1. Interestingly, PECAM-1 was also detected on human, mouse and rat solid tumor lines.
Recent studies suggest a role for PECAM-1 in the inflammatory process and leukocyte-endothelial interaction. PECAM-1 is an early and sensitive marker for tumor-induced angiogenesis. Several data have suggested that PECAM-1 may be involved in the process of angiogenesis in a developing vertebrate embryo as well as during metastases formation.
Applications Reported: This BMS137 antibody has been reported for use in ELISA, western blotting under non-reduced conditions, cell staining followed by both FACS and flow cytometric analysis, immunohistochemical staining of both frozen and FFPE tissues.
Applications Tested: This BMS137 antibody has been tested by western blot analysis and immunohistochemistry on human FFPE tissue using both low and high pH antigen retrieval at 30 µg/mL. It is recommended that the antibody be carefully titrated for optimal performance in the assay of interest.
Purity: >95%.
Â
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
