APC anti-mouse Integrin αVβ6
Integrins are heterodimeric transmembrane receptors that mediate cell-cell and cell-extracellular matrix adhesion. Integrin β6 associates exclusively with the αV subunit forming an αVβ6 complex that is expressed specifically on epithelial cells. Integrin αVβ6 is a receptor for multiple extracellular matrix (ECM) proteins, including tenascin, fibronectin, and vitronectin. It is also a receptor for the latency-associated peptide (LAP) of TGF-β and is involved in TGF-β activation. Its expression is upregulated during wound healing and in some cancers.
PRODUCT DETAILS
Clone: S20012E
Antibody Type: Monoclonal
Reactivity: Mouse
Format: Integrin alphaVbeta6
Host: Rat
Isotype: IgG2b, λ
Applications: FC - Quality tested
Regulatory Status: RUO
Note to Purchaser: This product is manufactured and supplied by BioLegend, Inc. under an agreement between BioLegend, Inc. and Cytek Biosciences, Inc. Information related to this product is provided by BioLegend, Inc.
APC anti-mouse Integrin αVβ6
Integrins are heterodimeric transmembrane receptors that mediate cell-cell and cell-extracellular matrix adhesion. Integrin β6 associates exclusively with the αV subunit forming an αVβ6 complex that is expressed specifically on epithelial cells. Integrin αVβ6 is a receptor for multiple extracellular matrix (ECM) proteins, including tenascin, fibronectin, and vitronectin. It is also a receptor for the latency-associated peptide (LAP) of TGF-β and is involved in TGF-β activation. Its expression is upregulated during wound healing and in some cancers.
PRODUCT DETAILS
Clone: S20012E
Antibody Type: Monoclonal
Reactivity: Mouse
Format: Integrin alphaVbeta6
Host: Rat
Isotype: IgG2b, λ
Applications: FC - Quality tested
Regulatory Status: RUO
Note to Purchaser: This product is manufactured and supplied by BioLegend, Inc. under an agreement between BioLegend, Inc. and Cytek Biosciences, Inc. Information related to this product is provided by BioLegend, Inc.
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Description
Integrins are heterodimeric transmembrane receptors that mediate cell-cell and cell-extracellular matrix adhesion. Integrin β6 associates exclusively with the αV subunit forming an αVβ6 complex that is expressed specifically on epithelial cells. Integrin αVβ6 is a receptor for multiple extracellular matrix (ECM) proteins, including tenascin, fibronectin, and vitronectin. It is also a receptor for the latency-associated peptide (LAP) of TGF-β and is involved in TGF-β activation. Its expression is upregulated during wound healing and in some cancers.
PRODUCT DETAILS
Clone: S20012E
Antibody Type: Monoclonal
Reactivity: Mouse
Format: Integrin alphaVbeta6
Host: Rat
Isotype: IgG2b, λ
Applications: FC - Quality tested
Regulatory Status: RUO
Note to Purchaser: This product is manufactured and supplied by BioLegend, Inc. under an agreement between BioLegend, Inc. and Cytek Biosciences, Inc. Information related to this product is provided by BioLegend, Inc.
